个人简介
毕业于中国科公司植物研究所果实逆境应答及生物控制技术研究组，获得博士学位，2008年获得“中国科公司优秀毕业生”，2011年入选杭州市‘131’人才计划，2013年入选“浙江省高校中青年学科带头人”。2018年入职美狮贵宾会，从事果实衰老的表观遗传学调控机制研究工作，在miRNA调控和DNA甲基化修饰方面研究果实衰老调控网络及机制。担任海南省食品营养与功能食品重点实验室副主任，受聘国家农产品保鲜工程技术中心（天津）特聘专家，国际特色果品产业科技创新院（浙江大学）特聘专家，国家自然科学基金通讯评审专家，北京市、浙江省、山东省、湖南省、广西壮族自治区、海南省、河南省和杭州市等10余省市自然科学基金评审专家。 Postharvest Biology and Technology，Scientia Horticulturae，Journal of Agriculture and Food Chemistry等SCI期刊审稿人。
教育背景
2005.9-2008.12 中国科公司植物研究所，发育生物学， 博士学位
2001.9-2004.6 山西农业大学 农公司，硕士学位
1995.9-1999.7 青岛农业大学（原莱阳农公司），植保系，学士学位
工作经历
2018.1-至今 美狮贵宾会，美狮贵宾会 教授
2008.12-2017.12 杭州师范大学，生命与环境科学公司
科研项目
1. 国家自然科学基金面上项目（31872160）2019-2022，主持
DNA甲基化介导Sly-miR171和靶基因LeCTR1调控番茄果实采后衰老的分子机制
2. 国家自然科学基金面上项目（31071836）2011-2013，主持
miRNA对非呼吸跃变型果实草莓采后衰老的分子调控机制研究
3. 海南省自然科学基金（2019RC127）2020-2023，（主持）
Sly-miR159介导LeACS8调控番茄果实采后衰老的表观遗传学机制研究
4. 海南省自然科学基金（322RC565）2022-2025，主持
Sly-miR171家族靶向GRAS24调控低温贮藏及冷链流通中果实冷害免疫机制研究
文章著作
（1）Wenhui Duan, Shuangshuang Shan, Xiaoyun Ye, Shen Ni, Qing Wang, Zhengke Zhang , Lanhuan Meng, Lisha Zhu, Jiali Yang, Hongmiao Song*, Xiangbin Xu*. Silencing Sly-miR159 accelerated preharvest ripening and delayed postharvest senescence of tomato fruit. Postharvest Biology and Technology. 2025, 219, 113243.
（2）Shen Ni, Wenhui Duan, Xiaoyun Ye, Zhengke Zhang, Lanhuan Meng, Jiali Yang, Lisha Zhu, Qing Wang, Hongmiao Song*, Xiangbin Xu*. Silencing of Sly-miR160a enhanced postharvest chilling tolerance of tomato fruit. Postharvest Biology and Technology. 2025, 227, 113598.
（3）Wenhui Duan, Jingrui Yan, Lei Li, Hongmiao Song, Lanhuan Meng, Zhengke Zhang, Xiangbin Xu*, Qing Wang*, Jiangkuo Li*. Silencing Sly-miR167a delayed preharvest ripening of tomato fruit. Postharvest Biology and Technology. 2024, 211, 112828.
（4）Xuanqi Wang, Shuzhi Yuan, Junyan Shi, Jieyu Lv, Yaqi Zhao, Hongshan Lu, Jinhua Zuo, Xiangbin Xu*, Bin Chen*, Qing Wang*.Transcriptomic and metabolomic analysis of the delay in chilling injury in green bell peppers (Capsicum annuum L.) by sodium hexametaphosphate. Postharvest Biology and Technology. 2024, 211, 112790.
（5）Hao Guo, Tian Tian, Jieyu Lv, Bangjin Yan, Shuzhi Yuan, Xiaodi Xu, Xiangbin Xu*, Xiaozhen Yue*, Qing Wang*. A Multi-Omic and physiological Investigation of the impact of 2-ethylhexylglycidylether (EHGE) on the postharvest senescence and yellowing of broccoli. LWT - Food Science and Technology. 2024, 205, 116530.
（6）Xiaoyun Ye, Wenhui Duan, Shen Ni, Jingrui Yan, Zhengke Zhang, Lanhuan Meng, Jiali Yang, Lisha Zhu, Hongmiao Song, Xiangbin Xu*, Qing Wang*. Overexpression of Sly-miR172a improved quality of tomato fruit by regulating MADS-box family. Scientia Horticulturae. 2024, 337, 113462.
（7）Francine Ngaffo Mekontso, Shuhui Wu, Ruizuo Fu, Wen Li, Lanhuan Meng, Qing Wang, Jiangkuo Li, Hongmiao Song, Xiangbin Xu*. Knockdown of Sly-miR160a using short tandem target mimic (STTM) enhanced expression of auxin signaling genes and delayed postharvest ripening of tomato fruit. Postharvest Biology and Technology. 2023, 198, 112271.
（8）Zhiqiang Wang, Qing Wang, Wenhui Duan, Lanhuan Meng, Jiangkuo Li, Hongmiao Song, Xiangbin Xu*. Overexpression of Sly-miR164a in tomato decreases expression of NAC and delays pre- and postharvest ripening of fruit. Postharvest Biology and Technology. 2023, 195, 112132.
（9）Lei Li, Xuanqi Wang, Jieyu Lv, Wenhui Duan, Taishan Huang, Keyan Zhao, Lanhuan Meng, Hongmiao Song, Qing Wang, Xiangbin Xu*, Jiangkuo Li*. Overexpression of Sly-miR167a delayed postharvest chilling injury of tomato fruit under low temperature storage. Postharvest Biology and Technology. 2023, 204,112420
（10）Junyan Shi, Taishan Huang, Ying Zhang, Zengting Xing, Xiaozhen Yue, Shuzhi Yuan, Hua Li, Xiangbin Xu*, Jinhua Zuo*, Qing Wang*. The effect of BVOCs produced by Lysinibacillus fusiformis and LED irradiation on pigment metabolism in stored broccoli. Food Chemistry 2023, 420, 136068.
（11）Lin Zhang, Zhiqiang Wang, Shixian Zeng, Shuzhi Yuan, Xiaozhen Yue, Tian Tian , Xiaoqian Zhu, Shufang Zheng, Xiangbin Xu*, Jinhua Zuo*, Qing Wang*. Browning mechanism in stems of fresh cut lettuce. Food Chemistry 2023, 405, 134575.
（12）Xuanqi Wang, Shuzhi Yuan, Junyan Shi, Yaqi Zhao, Hongshan Lu, Xu Jiang, Jieyv Lv, Xiangbin Xu*, Jinhua Zuo*, Qing Wang*. Hydroxypropyl cellulose reduces chilling injury in green bell pepper (Capsisum annuum L.) by regulating the activity and gene expression of enzymes involved in antioxidant and membrane lipid metabolism. Scientia Horticulturae 2023, 312, 111884.
（13）Xue Wan, Zhiqiang Wang, Wenhui Duan, Taishan Huang, Hongmiao Song and Xiangbin Xu*. Knockdown of Sly-miR164a Enhanced Plant Salt Tolerance and Improved Preharvest and Postharvest Fruit Nutrition of Tomato. International Journal of Molecular Science, 2023, 24, 4639.
（14）Zhiqiang Wang, Lin Zhang, Wenhui Duan, Wen Li, Qing Wang, Jiangkuo Li, Hongmiao Song, Xiangbin Xu*. Melatonin maintained higher contents of unsaturated fatty acid and cell membrane structure integrity in banana peel and alleviated postharvest chilling injury. Food chemistry. 2022, 397, 133836.
（15）Zengting Xing, Taishan Huang, Keyan Zhao, Lanhuan Meng, Hongmiao Song, Zhengke Zhang, Xiangbin Xu*, Songbai Liu*. Silencing of Sly-miR171d increased the expression of GRAS24 and enhanced postharvest chilling tolerance of tomato. Frontiers in plant science, 2022, 1006940.
（16）Keyan Zhao, Rulong Chen, Wenhui Duan, Lanhuan Meng, Hongmiao Song, Qing Wang, Jiangkuo Li, Xiangbin Xu*. Chilling injury of tomato fruit was alleviated under low-temperature storage by silencing Sly-miR171e with short tandem target mimic technology. Frontiers in Nutrition, 2022, 906227.
（17）Keyan Zhao, Hongmiao Song, Zhiqiang Wang, Zengting Xing, Jixin Tian, Qing Wang, Lanhuan Meng, Xiangbin Xu*. Knockdown of Sly-miR164a by short tandem target mimic (STTM) enhanced postharvest chilling tolerance of tomato fruit under low temperature storage. Postharvest Biology and Technology. 2022, 187, 111872
（18） Jixin Tian, Shiyin Xie, Peng Zhang, Qing Wang, Jiangkuo Li, Xiangbin Xu*. Attenuation of postharvest peel browning and chilling injury of banana fruit by Astragalus polysaccharides. Postharvest Biology and Technology. 2022, 184, 111783
（19）Wenhui Duan, Francine Ngaffo Mekontso, Wen Li, Jixin Tian, Jiangkuo Li, Qing Wang, Xiangbin Xu*. Alleviation of postharvest rib-edge darkening and chilling injury of carambola fruit by brassinolide under low temperature storage. Scientia Horticulturae. 2022, 299,110015
（20）Lin Zhang, Xiang Cao, Zhiqiang Wang, Zhengke Zhang, Jiangkuo Li, Qing Wang, Xiangbin Xu*. Brassinolide alleviated chilling injury of banana fruit by regulating unsaturated fatty acids and phenolic compounds. Scientia Horticulturae. 2022, 297,110922
（21）Shuangshuang Shan, Zhiqiang Wang, Huili Pu, Wenhui Duan, Hongmiao Song, Jiangkuo Li, Zhengke Zhang, Xiangbin Xu*. DNA methylation mediated by melatonin was involved in ethylene signal transmission and ripening of tomato fruit. Scientia Horticulturae. 2022, 291,110566
（22） Francine Ngaffo Mekontso, Wenhui Duan, El Hadji Malick Cisse, Tianye Chen, Xiangbin Xu*. Alleviation of postharvest chilling injury of carambola fruit by γ-aminobutyric acid: Physiological, biochemical and structural characterization. Frontiers in Nutrition. 2021.752583.
（23） Zhiqiang Wang, Huili Pu, Shuangshuang Shan, Peng Zhang, Jiangkuo Li, Hongmiao Song, Xiangbin Xu*. Melatonin enhanced chilling tolerance and alleviated peel browning of banana fruit under low temperature storage. Postharvest Biology and Technology. 2021, 179，111571.
（24） Zhiqiang Wang, Guofeng Yuan, Huili Pu, Shuangshuang Shan, Zhengke Zhang, Hongmiao Song, Xiangbin Xu*. 1-Methylcyclopropene suppressed the growth of Penicillium digitatum and inhibited the green mould in citrus fruit. Journal of Phytopathology. 2021;00: 1–8.
（25）Huili Pu, Shuangshuang Shan, Zhiqiang Wang, Wenhui Duan, Jixin Tian, Lin Zhang, Jiangkuo Li, Hongmiao Song, Xiangbin Xu*. Dynamic Changes of DNA Methylation Induced by Heat Treatment Were Involved in Ethylene Signal Transmission and Delayed the Postharvest Ripening of Tomato Fruit. Journal of Agriculture and Food Chemistry. 2020, 68, 89768986.
（26）Songbai Liu*, Xiuqin Qiu, Weiqiang Guo, Jinli Li, Qian Su, Jiahui Du, Hejuan Hu, Xiaoxiao Wang, Yaohua Song, Xiao Lou, Xiangbin Xu*. Transcriptome Analysis of FEN1 Knockdown HEK293T Cell Strain Reveals Alteration in Nucleic Acid Metabolism, Virus Infection, Cell Morphogenesis and Cancer Development. Combinatorial Chemistry & High Throughput Screening. 2019, 22, 6: 379-386.
（27） Xiangbin Xu, Kang Guo, Wenwen Liang, Qifeng Chen, Jun Shi, Bo Shen. Quantitative proteomics analysis of proteins involved in leaf senescence of Oryza sativa L. Plant Growth Regulation. 2018, 8（2）341-349.
（28）Xiangbin Xu, Huanhuan Lei, Xiuyan Ma, Tongfei Lai, Hongmiao Song, Xuequn Shi, Jiangkuo Li. Antifungal activity of 1-methylcyclopropene (1-MCP) against anthracnose (Colletotrichum gloeosporioides) in postharvest mango fruit and its possible mechanisms of action. International Journal of Food Microbiology. 2017, 241, 1-6.
（29） Jiangkuo Li, Huanhuan Lei, Hongmiao Song, Tongfei Lai, Xiangbin Xu*, Xuequn Shi. 1-methylcyclopropene (1-MCP) suppressed blue mould of postharvest apple fruit by direct inhibiting the growth of Penicillium expansum. Postharvest Biology and Technology. 2017,125, 59-64.
（30）Jiangkuo Li, Tongfei Lai, Hongmiao Song, Xiangbin Xu*. MiR164 is involved in Delaying Senescence of Strawberry (Fragaria ananassa) Fruit by Negatively Regulating NAC Transcription Factor Genes under Low Temperature. Russian Journal of Plant Physiology, 2017, Vol. 64
（31） Xiangbin Xu, Xiuyan Ma, Huanhuan Lei, Lili Yin, Xuequn Shi, Hongmiao Song. MicroRNAs play an important role in the regulation of strawberry fruit senescence in low temperature. Postharvest Biology and Technology. 2015, 108: 39-47.
（32）Xiangbin Xu, Xiuyan Ma, Huanhuan Lei, Hongmiao Song, Qicai Ying, Maojun Xu, Songbai Liu and Huizhong Wang. Proteomic analysis reveals the mechanisms of Mycena dendrobii promoting transplantation survival and growth of tissue culture seedlings of Dendrobium officinale. Journal of Applied Microbiology. 2015. 118, 1444-1455.
（33）Xiangbin Xu, Chunling Wang, Xiuyan Ma, Yuanyuan Pan, Qicai Ying, Hongmiao Song and Huizhong Wang. Overexpression of DnWRKY29 in tobacco impaired plants tolerance to salt and drought stresses. Russian journal of plant physiology. 2015, 62(1):1-8.
（34）Xiangbin Xu, Haiqi Bai, Chaoping Liu, Eryong Chen, Qifeng Chen, Jieyun Zhuang, Bo Shen. Genome-Wide Analysis of MicroRNAs and Their Target Genes Related to Leaf Senescence of Rice. PLOS ONE. 2014, 9(12): e114313.
（35）Xiangbin Xu, Qinghua Jiang, Xiuyan Ma, Qicai Ying, Bo Shen, Yongsheng Qian, Hongmiao Song and Huizhong Wang. Deep sequencing identify tissue-specific microRNAs and their target genes involved in tanshinones biosynthesis in Salvia miltiorrhiza. PLOS ONE. 2014, 9(11): e111679.
（36）Xiangbin Xu, Yuanyuan Pan, Chunling Wang, Qicai Ying, Hongmiao Song and Huizhong Wang. Overexpression of DnWRKY11 enhanced salt and drought stress tolerance of transgenic tobacco. Biologia. 2014, 69(7): 1-7.
（37）Xiangbin Xu, Lili Yin, Qicai Ying, Hongmiao Song, Dawei Xue, Tongfei Lai, Maojun Xu, Bo Shen, Huizhong Wang, Xuequn Shi. High-throughput sequencing and degradome analysis identify mirnas and their targets involved in fruit senescence of Fragaria ananassa. PLOS ONE. 2013, 8(8): e70959.
（38）Hongmiao Song, Huizhong Wang and Xiangbin Xu*. Overexpression of AtHsp90.3 in Arabidopsis thaliana impairs plant tolerance to heavy metal stress. Biologia Plantarum, 2012, 56:197-199
（39）Hongmiao Song, Xiangbin Xu*, Hua Wang and Yuezhi Tao. Reducing Protein Carbonylation Caused by Aluminum and Proton Toxicity with Salicylic Acid in Barley. Russian Journal of plant physiology. 2011, 58(4): 653-659.
（40）Xiangbin Xu, Jufang Bian, Songbai Liu, Hongmiao Song, Nongnong Shi, Yuezhi Tao and HuiZhong. Flower-specific expression of Arabidopsis PCS1 driven by AGAMOUS second intron in tobacco decreased the transgenic plants fertility. Molecular Breeding. 2011, 27 (3): 337-346.
（41）Xiangbin Xu, Hongmiao Song, Zhenhua Zhou, Nongnong Shi, Qicai Ying and Huizhong Wang. Functional characterization of AtHsp90.3 in Saccharomyces cerevisiae and Arabidopsis thaliana under heat stress. Biotechnology Letters. 2010, 32: 979-987.
（42）Xiangbin Xu, Sai Guo, Kai Chen, Hongmiao Song, Junjun Liu, Longbiao Guo, Qian Qian and Huizhong Wang. A 796 bp PsPR10 gene promoter fragment increased root-specific expression of the GUS reporter gene under the abiotic stresses and signal molecules in tobacco. Biotechnology Letters. 2010, 32（10）:1533-1539.
（43）Zhulong Chan#, Qing Wang#, Xiangbin Xu#, Xianghong Meng, Guozheng Qin, Boqiang Li and Shiping Tian. Functions of defense-related proteins and dehydrogenases in resistance response induced by salicylic acid in sweet cherry fruits at different maturity stages. Proteomics. 2008, 8(22): 4791-4807（#并列第一作者)
（44）Xiangbin Xu, Guozheng Qin and Shiping Tian. Effect of microbial biocontrol agents on alleviating oxidative damage of peach fruit subjected to fungal pathogen. International Journal of Food Microbiology. 2008, 126, 153-158.
（45）Xiangbin Xu and Shiping Tian. Salicylic acid alleviated pathogen-induced oxidative stress in harvested sweet cherry fruit. Postharvest Biology and Technology. 2008, 49, 379-385.
（46）Xiangbin Xu and Shiping Tian. Reducing oxidative stress in sweet cherry fruit by Pichia membranaefaciens: a possible mode of action against Penicillium expansum. Journal of Applied Microbiology. 2008, 105(4): 1170-1177.
（47）Xiangbin Xu, Zhulong Chan, Yong Xu and Shiping Tian. Effect of Pichia membranaefaciens combined with salicylic acid on controlling brown rot in peach fruit and the mechanisms involved. Journal of the Science of Food and Agriculture. 2008, 88, 1786-1793.
获奖
科技进步奖三等奖，杭州市（2014）
科技进步奖三等奖，海南省（2015）
科学技术进步奖二等奖，天津市（2020）
专利
1.ZL201510338443.6
2.ZL201711303338.4
3.ZL201711303356.2
4.ZL201711303322.3
5.ZL201920601010.9
承担教学
（1）本科生教学：《动植物检验检疫》，《食品分子生物学技术》，《食品安全检测和控制综合实践》
（2）研究生课程：《食品加工与贮藏专题》，《分子生物学实验技术》，《食品安全与风险分析》，《专业前沿研讨》，《农产品加工与贮藏工程》，《食品安全检测和控制技术》
公司产品
目前在读博士研究生1人、硕士研究生2人，毕业研究生30人，欢迎对采后分子生物学研究领域感兴趣的同学报考我的研究生。
