个人简介
刘星，博士，教授，博士/硕士生导师，美狮贵宾会高层次引进人才，美狮贵宾会有毒有害物检测技术团队负责人，海南省拔尖人才，海南省科协青年科技英才，海南省食品安全委员会专家，国家市场监管重点实验室（热带果蔬质量与安全）学术带头人及学术委员会委员，海南省食品安全地方标准审评委员会委员。聚焦热带食品安全与健康领域，开展热带农产品安全检测与质量控制技术及产品开发，以及癌症等疾病标志物的快速诊断技术与产品开发等研究。主持国家自然科学基金、海南省重点研发计划等多项国家级和省部级课题。以第一作者/通讯作者发表SCI论文60余篇，并担任国内外多个学术期刊的客座编辑或青年编委。
教育背景
2012.09-2015.06 南昌大学，食品科学与工程专业，博士学位
2013.12-2014.12 加州大学戴维斯分校，联合培养博士
2009.09-2012.06 南昌大学，营养与食品卫生学专业，硕士学位
2005.09-2009.06 南昌大学，食品科学与工程专业，学士学位
工作经历
2022.01-至今 美狮贵宾会，美狮贵宾会，教授
2019.01-2021.12 美狮贵宾会，美狮贵宾会，副教授
2016.01-2018.12 美狮贵宾会，美狮贵宾会，讲师
2015.11-2020.11 美狮贵宾会，美狮贵宾会，教授（高聘）
科研项目
1. 国家自然科学基金地区项目，No. 32560606，2026-2029，主持
2. 国家自然科学基金青年项目，No. 32102067，2022-2024，主持
3. 国家自然科学基金地区项目，No. 31760493，2018-2021，主持
4. 海南省重点研发计划项目，No. ZDYF2020157，2020-2022，主持
5. 海南省自然科学基金高层次人才项目，No. 2019RC119，2020-2022，主持
文章著作
[1] Chen, X., He, Z., Jiao, S., Sun, Z., Zhang, S., Liu, X.* (2025). Colorimetric-fluorescent dual-mode nanosensor-powered enzyme immunoassay for ochratoxin A via alkaline phosphatase-mediated silver nanoparticle growth and fluorescence inner filter effect. Journal of Hazardous Materials, 494, 138539.
[2] Zhang, Y., He, Z., Sun, Z., Zhang, S., Liu, X.* (2025). Genetic engineering-powered dual-mode lateral flow immunosensor for colorimetric and fluorescent detection of ochratoxin A in pepper. Journal of Hazardous Materials, 489, 137636.
[3] Mao, F., Yang, X., He, Z., Sun, Z., Zhang, S., Liu, X.* (2025). Mimotope peptides for nanobodies: A nontoxic alternative to ochratoxin A and its application in chemiluminescence immunoassays for analysis of pepper samples. Food Chemistry, 465, 142061.
[4] Chen, X., He, Z., Huang, X., Sun, Z., Cao, H., Wu, L., Zhang S, Hammock B.D., Liu, X.* (2025). Illuminating the path: aggregation-induced emission for food contaminants detection. Critical Reviews in Food Science and Nutrition, 65(5), 856-883.
[5] Xie, X., Yang, X., Zhang, Y., Mao, F., He, Z., Sun, Z., Zhang S, Liu, X.* (2024). Ready-to-use ratiometric bioluminescence immunosensor for detection of ochratoxin a in pepper. Biosensors and Bioelectronics, 259, 116401.
[6] Wang, Z., Xie, X., He, Z., Sun, Z., Zhang, Y., Mao, F., Pei, H., Zhang, S., Hammock, B.D. Liu, X.* (2024). Development of shark single domain antibodies specific for human α-fetoprotein and the multimerization strategy in serum detection. Analytical Chemistry, 96(10), 4242-4250.
[7] Jiao, S., Chen, X., He, Z., Wu, L., Xie, X., Sun, Z., Zhang, S., Cao, H., Hammock, B.D., Liu, X.* (2024). Colorimetric and surface-enhanced Raman scattering dual-mode lateral flow immunosensor using phage-displayed shark nanobody for the detection of crustacean allergen tropomyosin. Journal of Hazardous Materials, 468, 133821.
[8] Xie, X., He, Z., Sun, Z., Zhang, S., Cao, H., Hammock, B.D., Liu, X.* (2024). Shark anti-idiotypic variable new antigen receptor specific for an alpaca nanobody: Exploration of a nontoxic substitute to ochratoxin A in immunoassay. Journal of Hazardous Materials, 477, 135264.
[9] Jiao, S., Xie, X., He, Z., Sun, Z., Wang, Z., Zhang, S., Cao, H., Hammock, B.D., Liu, X.* (2024). Lateral flow immunochromatographic assay for competitive detection of crustacean allergen tropomyosin using phage-displayed shark single-domain antibody. Journal of Agricultural and Food Chemistry, 72(3), 1811-1821.
[10] Liu, X., Li, J., Chen, R., Xie, X., Mao, F., Sun, Z., He, Z., Cao, H., Zhang, S., Liu, X.* (2024). Colorimetric and chemiluminescent enzyme immunoassays based on the alkaline phosphatase-tagged single-chain variable fragment fusion tracer for detecting zearalenone in agro-products. Food Chemistry, 443, 138569.
[11] Mao, F., He, Z., Sun, Z., Zhang, S., Cao, H., Liu, X.* (2024). Plasmonic enzyme immunoassay via nanobody-driven controllable aggregation of gold nanoparticles for detection of ochratoxin A in pepper. Food Chemistry, 453, 139623.
[12] Yang, X., Sun, Z., He, Z., Xie, X., Liu, X.* (2023). Combination of nanobody and peptidomimetic to develop novel immunoassay platforms for detecting ochratoxin A in cereals. Food Chemistry, 429, 137018.
[13] Su, B., Zhang, Z., Sun, Z., Tang, Z., Xie, X., Chen, Q., Cao, H., Yu, X., Xu, Y., Liu, X.*, Hammock, B. D. (2022). Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detection of ochratoxin A. Journal of hazardous materials, 422, 126838.
[14] Xie, X., He, Z., Qu, C., Sun, Z., Cao, H., Liu, X.* (2022). Nanobody/NanoBiT system-mediated bioluminescence immunosensor for one-step homogeneous detection of trace ochratoxin A in food. Journal of Hazardous Materials, 437, 129435.
[15] Xie, G., Lu, Y., Li, W., He, Z., Sun, Z., Xie, X., Liu, X.* (2022). Simultaneous heptamerization of nanobody and alkaline phosphatase by self-assembly and its application for ultrasensitive immunodetection of small molecular contaminants in agro-products. Food Control, 141, 109156.
获奖
[1] 海南省优秀硕士学位论文导师，HNS2023-43，海南省教育厅（2024）
[2] 海南省优秀硕士学位论文导师，HNS2020-29，海南省教育厅（2020）
专利
[1] 刘星; 文莉; 孙志昶; 杨迅; 贺贞云; 曹宏梅. 一种赭曲霉毒素A的抗原模拟肽及编码核酸分子和应用, 2023-12-08, 中国, ZL 2023 10610666.8.
[2] 刘星; 谢晓霞; 孙志昶; 贺贞云; 王哲铭. 一种鲨源赭曲霉毒素A抗独特型纳米抗体及其制备方法和应用, 2024-06-28, 中国, ZL 2023 1 1264113.8.
[3] 曹宏梅; 李林芝; 刘星; 李莹. 一种检测赭曲霉毒素A的电致化学发光修饰电极的制备方法及传感器, 2025-04-18, 中国, ZL 2022 1 1628172.4.
承担教学
1、本科生课程：《食品分析》、《食品分析实验》、《食品免疫学与技术》
2、硕士研究生课程：《食品安全检验和控制技术》、《食品安全风险与评估》
3、博士研究生课程：《食品安全专题》
公司产品
目前指导在站博士后1人，在读博士研究生1人，硕士研究生5人，毕业博士研究生2人和硕士研究生15人，热烈欢迎具有材料科学与工程、分析化学、有机化学、食品科学与工程、食品质量与安全、微生物学、医学检验、免疫学、生物信息学、分子生物学、合成生物学、人工智能等专业背景的同学报考加入Liu Lab。
